A postdoctoral position is available in the laboratory of Dr. Young-Goo Han in the Department of Developmental Neurobiology/Neurobiology and Brain Tumor Program at St. Jude Children's Research Hospital. The Han laboratory studies the biology of primary cilia and how cilia-dependent signaling regulates cell behavior in normal development and disease, with particular emphasis on brain development, brain tumors, neurodevelopmental disorders, and neurodegenerative diseases.
The Han laboratory has made important contributions to understanding the roles of primary cilia and Hedgehog signaling in neural stem cell formation, cerebellar development, medulloblastoma, neocortical growth and folding, and cilia-dependent regulation of translation and the cell cycle. Applicants who are interested in fundamental mechanisms by which primary cilia or mitochondria control cellular homeostasis and signaling are encouraged to apply. We use a broad range of approaches, including human pluripotent stem cells, brain organoids, genome editing, high-resolution imaging, single-cell sequencing, spatial transcriptomics, epigenomics, and proteomics, as well as a unique mouse model in which neural progenitors acquire key features of human neural progenitors, driving expansion and folding of the normally small, smooth mouse cortex. Research areas may include:G2 is the world's largest and most trusted software marketplace. When you join G2, youre joining the industrys leading team that helps businesses reach their peak potential by powering decisions and strategies with trusted insights from real software users. We have joined...
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